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2018/5/21 2:16:25 | Browse: 774 | 下载: 739
Publication Name |
世界华人消化杂志 |
手稿编号 |
35946 |
手稿来源省、自治区或特别行政区 |
湖南省 |
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Received |
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2018-04-04 04:26 |
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Peer-Review Started |
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2018-04-05 02:36 |
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To Make the First Decision |
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2018-04-23 06:25 |
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Return for Revision |
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2018-04-24 00:35 |
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修回稿 |
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2018-05-07 01:58 |
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Second Decision |
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2018-05-09 11:30 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-05-09 14:44 |
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预出版 |
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2018-05-09 14:44 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2018-05-14 09:18 |
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在线出版 |
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2018-05-18 08:45 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化基础研究 |
手稿栏目类型 |
述评 |
文章标题 |
HDAC6在消化系统原发恶性肿瘤中的研究进展
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手稿来源 |
约稿 |
所有作者列表 |
张诗岚, 李琛, 刘德良, 谭玉勇 |
基金项目及其编号 |
基金项目名称 |
基金编号 |
国家临床重点专科项目 |
(2012)650 |
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通讯作者 |
谭玉勇, 博士, N/A, 410011, 湖南省长沙市人民中路139号, 中南大学湘雅二医院消化内科. tanyuyong@csu.edu.cn |
关键词 |
蛋白质翻译后修饰; 组蛋白去乙酰化酶6; 消化系统恶性肿瘤 |
核心内容提要 |
随着肿瘤生物学研究的不断进展, 遗传学和表观遗传学改变引起癌基因活化和抑癌基因失活是肿瘤发生的核心生物学进程. 蛋白质去乙酰化修饰是表观遗传学改变中的重要方式, 可通过多种途径参与肿瘤的形成. 本文通过阐述组蛋白去乙酰化酶6在消化系统恶性肿瘤中的作用及其机制, 旨在为消化系统恶性肿瘤的防治提供新的靶点. |
出版日期 |
2018-05-18 08:45 |
引文著录 |
张诗岚, 李琛, 刘德良, 谭玉勇. HDAC6在消化系统原发恶性肿瘤中的研究进展. 世界华人消化杂志 2018 |
URL |
http://www.wjgnet.com/1009-3079/full/v26/i14/827.htm |
DOI |
http://dx.doi.org/10.11569/wcjd.v26.i14.827 |
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