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2018/9/27 8:40:56 | Browse: 768 | 下载: 713
Publication Name |
世界华人消化杂志 |
手稿编号 |
36257 |
手稿来源省、自治区或特别行政区 |
浙江省 |
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Received |
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2018-08-02 08:39 |
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Peer-Review Started |
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2018-08-02 09:30 |
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To Make the First Decision |
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2018-08-14 09:12 |
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Return for Revision |
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2018-08-16 10:26 |
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修回稿 |
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2018-08-29 09:19 |
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Second Decision |
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2018-09-04 00:31 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-09-06 07:33 |
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预出版 |
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2018-09-06 07:33 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2018-09-25 10:11 |
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在线出版 |
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2018-09-27 07:30 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化基础研究 |
手稿栏目类型 |
基础研究 |
文章标题 |
miR-144-3p靶向调控ABCG2信号通路对胃癌细胞侵袭和迁移的影响
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手稿来源 |
自由来稿 |
所有作者列表 |
吕弢, 俞兴旺, 胡静, 周东辉 |
基金项目及其编号 |
基金项目名称 |
基金编号 |
国家自然科学基金面上项目 |
81272680 |
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通讯作者 |
吕弢, 本科, 主治医师, 321300, 浙江省永康市浙江省永康市金山西路599号, 永康市第一人民医院监所门诊部. wangbinly8@126.com |
关键词 |
miR-144-3p; ATP结合转运蛋白G家族成员2; 胃癌细胞; 基质金属蛋白酶; 侵袭和迁移 |
核心内容提要 |
本实验首次证实了ATP结合转运蛋白G家族成员2(ATP-binding transporter G family member 2, ABCG2)是miR-144-3p的靶基因, 且发现miR-144-3p能够抑制人胃癌(gastric cancer, GC)HGC-27细胞侵袭和迁移能力, 其作用机制与miR-144-3p通过靶向负调控ABCG2的表达, 介导基质金属蛋白酶2和基质金属蛋白酶9蛋白活性有关. 本研究以期为GC临床治疗及预后提供新的作用靶点. |
出版日期 |
2018-09-27 07:30 |
引文著录 |
吕弢, 俞兴旺, 胡静, 周东辉. miR-144-3p靶向调控ABCG2信号通路对胃癌细胞侵袭和迁移的影响. 世界华人消化杂志 2018 |
URL |
http://www.wjgnet.com/1009-3079/full/v26/i28/1635.htm |
DOI |
http://dx.doi.org/10.11569/wcjd.v26.i28.1635 |
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