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2018/9/25 2:11:14 | Browse: 778 | 下载: 678
Publication Name |
世界华人消化杂志 |
手稿编号 |
36268 |
手稿来源省、自治区或特别行政区 |
湖北省 |
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Received |
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2018-08-03 02:58 |
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Peer-Review Started |
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2018-08-03 11:59 |
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To Make the First Decision |
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2018-08-14 09:13 |
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Return for Revision |
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2018-08-16 11:18 |
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修回稿 |
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2018-08-18 02:41 |
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Second Decision |
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2018-09-04 00:31 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-09-06 07:33 |
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预出版 |
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2018-09-06 07:33 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2018-09-18 04:03 |
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在线出版 |
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2018-09-22 11:12 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化肿瘤学 |
手稿栏目类型 |
基础研究 |
文章标题 |
Wee1抑制剂MK-1775对GBC-SD细胞系胆囊癌干细胞样细胞自我更新的影响
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手稿来源 |
自由来稿 |
所有作者列表 |
石程剑, 田锐, 王敏, 赵炎, 秦仁义 |
基金项目及其编号 |
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通讯作者 |
秦仁义, 博士, 教授, 主任医师, 430030, 湖北省武汉市解放大道1095号, 武汉同济医院胆胰外科. 623657559@qq.com |
关键词 |
MK-1775;胆囊癌;肿瘤干细胞;自我更新 |
核心内容提要 |
原发性胆囊癌早期诊断困难, 恶性程度高, 肿瘤进展快, 预后较差. 目前研究表明肿瘤干细胞是肿瘤发生发展发的根本原因. 本研究通过体外和体内实验观察到MK-1775对胆囊癌干细胞样细胞自我更新具有抑制作用, 有望成为治疗胆囊癌的靶向药物之一. |
出版日期 |
2018-09-22 11:12 |
引文著录 |
石程剑, 田锐, 王敏, 赵炎, 秦仁义. Wee1抑制剂MK-1775对GBC-SD细胞系胆囊癌干细胞样细胞自我更新的影响. 世界华人消化杂志 2018 |
URL |
http://www.wjgnet.com/1009-3079/full/v26/i27/1586.htm |
DOI |
http://dx.doi.org/10.11569/wcjd.v26.i27.1586 |
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