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2019/1/9 3:18:54 | Browse: 736 | 下载: 770
Publication Name |
世界华人消化杂志 |
手稿编号 |
36459 |
手稿来源省、自治区或特别行政区 |
山东省 |
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Received |
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2018-10-10 05:06 |
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Peer-Review Started |
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2018-10-10 05:47 |
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To Make the First Decision |
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2018-10-17 05:32 |
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Return for Revision |
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2018-10-20 05:24 |
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修回稿 |
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2018-10-31 13:54 |
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Second Decision |
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2018-11-16 03:43 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-11-16 04:23 |
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预出版 |
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2018-11-16 04:23 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2019-01-04 09:41 |
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在线出版 |
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2019-01-08 08:50 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化内科学 |
手稿栏目类型 |
文献综述 |
文章标题 |
肠道微生物与自身免疫性肝病研究进展与评价
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手稿来源 |
约稿 |
所有作者列表 |
池肇春 |
基金项目及其编号 |
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通讯作者 |
池肇春, 本科, 教授, 主任医师, 266035, 山东省青岛市胶州路1号, 青岛市市立医院消化内科. c.z.chow@163.com |
关键词 |
自身免疫性肝炎; 原发性硬化性胆管炎; 原发性胆汁性胆管炎; 先天免疫; 肠菌生态失衡; 黏膜屏障; 益生菌 |
核心内容提要 |
肠道微生物是微生物抗原和活化免疫细胞的储存库, 这些细胞参与了多种全身免疫介导的疾病的发病机制. 自身免疫性肝炎可能由肠道功能障碍、肠通透性增加以及微生物和自身抗原之间的分子模拟引起或维持. 多种药物、分子、饮食和益生菌干预可以改变肠道微生物群并减弱免疫应答. 肠道微生物在自身免疫性肝病(autoimmune liver disease, AILD)中的作用值得进行深入的研究, 并且将寻求新的治疗方法, 如抗生素、益生菌、粪便移植有望成为治疗的新靶点, 以改善AILD的预后. |
出版日期 |
2019-01-08 08:50 |
引文著录 |
池肇春. 肠道微生物与自身免疫性肝病研究进展与评价. 世界华人消化杂志 2018 |
URL |
https://www.wjgnet.com/1009-3079/full/v27/i1/50.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v27.i1.50 |
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