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2019/11/5 10:02:48 | Browse: 930 | 下载: 978
Publication Name |
世界华人消化杂志 |
手稿编号 |
37076 |
手稿来源省、自治区或特别行政区 |
海南省 |
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Received |
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2019-06-10 02:04 |
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Peer-Review Started |
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2019-06-16 11:56 |
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To Make the First Decision |
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2019-07-04 00:57 |
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Return for Revision |
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2019-08-01 10:06 |
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修回稿 |
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2019-08-13 16:09 |
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Second Decision |
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2019-08-16 09:19 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2019-08-26 03:27 |
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预出版 |
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2019-08-26 03:27 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2019-09-06 05:24 |
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在线出版 |
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2019-09-07 10:13 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化基础研究 |
手稿栏目类型 |
基础研究 |
文章标题 |
ELMO1基因甲基化检测在胃癌早期诊断中的价值
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手稿来源 |
自由来稿 |
所有作者列表 |
宋健, 黎萍, 袁桂红, 贾真, 张荣琳, 王发宝, 钟国柄, 李依倪, 钟敦璟 |
基金项目及其编号 |
基金项目名称 |
基金编号 |
海南省科技厅社会发展重点研发项目 |
No. ZDYF2017118 |
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通讯作者 |
宋健, 博士, 主任医师, 570123, 秀英区长滨西四街6号, 海南省肿瘤医院消化内镜科. songjian0532@sina.com |
关键词 |
ELMO1基因;甲基化;胃癌;胃液:诊断 |
核心内容提要 |
本研究选择慢性非萎缩性胃炎、萎缩性胃炎、早期胃癌及进展期胃癌患者的组织标本及胃液标本,利用甲基化特异性PCR的方法研究了ELMO1基因甲基化异化的发生情况,结果是:ELMO1基因甲基化异化在胃癌发生率达90%以上,早期胃癌为86.7%,并且在胃液标本的甲基化检出率与组织标本具有一致性。结果提示ELMO1基因甲基化可作为胃癌的分子诊断靶标,通过胃液检测ELMO1基因甲基化可用于胃癌的早期诊断。 |
出版日期 |
2019-09-07 10:13 |
引文著录 |
宋健, 黎萍, 袁桂红, 贾真, 张荣琳, 王发宝, 钟国柄, 李依倪, 钟敦璟. ELMO1基因甲基化检测在胃癌早期诊断中的价值. 世界华人消化杂志 2019 |
URL |
https://www.wjgnet.com/1009-3079/full/v27/i17/1055.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v27.i17.1055 |
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