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        2021/12/8 12:26:55 | Browse: 649 | 下载: 757
    
    
        
            
                | Publication Name | 
                世界华人消化杂志 | 
            
            
                | 手稿编号 | 
                38496 | 
            
            
                | 手稿来源省、自治区或特别行政区 | 
                北京市 | 
            
        
        
    
        
            
                
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        2021-09-27 04:21 | 
    
    
        
            
                
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        2021-12-07 09:44 | 
    
            
                
                    
                        
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                            在线出版 | 
                         
                     
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                2021-12-08 11:59 | 
            
        
        
            
                | ISSN | 
                1009-3079 (print) and 2219-2859 (online) | 
            
            
                | 开放获取 | 
                This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ | 
            
            
                | 版权 | 
                © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. | 
            
                    
                        | Article Reprints | 
                        
                            For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
                         | 
                    
            
            
                | Permissions | 
                
                    For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
                 | 
            
            
            
                | Publisher | 
                Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | 
            
            
                | 网址 | 
                http://www.wjgnet.com | 
            
        
    
        | 专业类型 | 
        消化病理学 | 
    
    
        | 手稿栏目类型 | 
        文献综述  | 
    
    
        | 文章标题 | 
        
                    Paneth cell与肠道健康
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        | 手稿来源 | 
        自由来稿 | 
    
    
        | 所有作者列表 | 
        韩怡敏, 高晗, 华嵘暄, 梁宸, 郭玥昕, 尚宏伟, 路欣, 徐敬东 | 
    
    
        | 基金项目及其编号 | 
        
                    
                        
                            
                                | 基金项目名称 | 
                                基金编号 | 
                             
                        
                        
                                    
                                        | 国家自然科学基金资助项目 | 
                                        No.81274173 | 
                                     
                                    
                                        | 国家自然科学基金资助项目 | 
                                        No.81673671 | 
                                     
                                    
                                        | 国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项课题 | 
                                        No.2016YFC1306305 | 
                                     
                        
                     
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        | 通讯作者 | 
        徐敬东, 博士, 副教授, 100069, 右安门外西头条10号, 首都医科大学基础医学院生理学与病理生理学系. xujingdong@163.com | 
    
    
        | 关键词 | 
        潘氏细胞; 分化; 功能; 炎症性肠病; 结直肠癌 | 
    
    
        | 核心内容提要 | 
        潘氏细胞(paneth cell, PC)是由肠道干细胞分化并定居于小肠隐窝底部的分泌性细胞, 当肠道微环境发生改变时, 可分泌多种抗菌肽和细胞因子以调节肠道稳态、肠道干细胞增殖分化和修复损伤肠组织, 对维持肠道的稳态与健康至关重要. | 
    
            
                | 出版日期 | 
                2021-12-08 11:59 | 
            
    
        | 引文著录 | 
        韩怡敏, 高晗, 华嵘暄, 梁宸, 郭玥昕, 尚宏伟, 路欣, 徐敬东. Paneth cell与肠道健康. 世界华人消化杂志 2021; 29(23): 1362-1372 | 
    
            
                | URL | 
                https://www.wjgnet.com/1009-3079/full/v29/i23/1362.htm | 
            
            
                | DOI | 
                https://dx.doi.org/10.11569/wcjd.v29.i23.1362 | 
            
    
    
                
        
     
 
                 
             
         
        
    
        
        
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