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2023/4/7 13:54:58 | Browse: 261 | 下载: 258
Publication Name |
世界华人消化杂志 |
手稿编号 |
39303 |
手稿来源省、自治区或特别行政区 |
北京市 |
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Received |
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2022-12-12 08:08 |
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Peer-Review Started |
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2022-12-13 02:01 |
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To Make the First Decision |
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Return for Revision |
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2023-01-17 07:09 |
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修回稿 |
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2023-01-22 10:38 |
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Second Decision |
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2023-03-16 12:37 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2023-03-20 17:22 |
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预出版 |
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2023-03-20 17:22 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2023-04-07 10:04 |
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在线出版 |
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2023-04-07 13:49 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化中医药学 |
手稿栏目类型 |
基础研究 |
文章标题 |
基于网络药理学研究一贯煎治疗肝纤维化的有效成分及作用机制
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手稿来源 |
自由来稿 |
所有作者列表 |
崔欣怡, 姜晓丹, 李汶航, 张睿, 油红捷, 唐佐青, 马赟, 杨铮, 车念聪, 刘文兰 |
基金项目及其编号 |
基金项目名称 |
基金编号 |
国家自然科学基金 |
81573879 |
北京市自然科学基金 |
7182021 |
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通讯作者 |
刘文兰, 博士, 副主任医师, 教授, 100069, 北京市丰台区右安门外西头条10号, 首都医科大学中医药学院. wenlanliu1900@126.com |
关键词 |
一贯煎; 肝纤维化; 网络药理; 重启随机游走 |
核心内容提要 |
本研究基于网络药理学方法, 通过构建一贯煎-肝纤维化蛋白互作子网络, 应用重启随机游走算法探索一贯煎治疗肝纤维化的作用机制, 实验验证表明一贯煎抗肝纤维化作用与调控STAT6/PPAR-γ通路促进巨噬细胞向M2型极化有关. |
出版日期 |
2023-04-07 13:49 |
引文著录 |
崔欣怡, 姜晓丹, 李汶航, 张睿, 油红捷, 唐佐青, 马赟, 杨铮, 车念聪, 刘文兰. 基于网络药理学研究一贯煎治疗肝纤维化的有效成分及作用机制. 世界华人消化杂志 2023; 31(7): 256-267 |
URL |
https://www.wjgnet.com/1009-3079/full/v31/i7/256.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v31.i7.256 |
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