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2023/4/28 11:16:22 | Browse: 286 | 下载: 274
Publication Name |
世界华人消化杂志 |
手稿编号 |
39394 |
手稿来源省、自治区或特别行政区 |
湖北省 |
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Received |
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2023-03-05 01:49 |
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Peer-Review Started |
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2023-03-05 02:20 |
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2023-03-27 13:47 |
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2023-03-29 14:59 |
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Second Decision |
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2023-04-20 14:45 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2023-04-24 16:58 |
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预出版 |
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2023-04-24 16:58 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2023-04-28 03:27 |
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在线出版 |
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2023-04-28 11:04 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化感染病学 |
手稿栏目类型 |
文献综述 |
文章标题 |
HBV慢性感染诱导的染色体超倍化及靶向治疗策略
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手稿来源 |
自由来稿 |
所有作者列表 |
施旭佳, 尧晨光, 李涵泺, 魏艳红, 胡康洪 |
基金项目及其编号 |
基金项目名称 |
基金编号 |
2022年湖北省科技厅重点研发计划立项项目 |
2022BCA018 |
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通讯作者 |
胡康洪, 其他, 教授, 430068, 湖北省武汉市南李路28号, 湖北工业大学中德生物医学中心教育部及国家外专局“细胞调控与分子药物学科111创新引智基地”生物工程与食品工程学院. hukh@hbut.edu.cn |
关键词 |
乙型肝炎病毒; 慢性乙型肝炎病毒感染; 多倍体; 非整倍化; 超倍化; 原发性肝细胞癌 |
核心内容提要 |
本文综述了乙型肝炎病毒通过上调Polo样激酶1/蛋白调节因子1和细胞周期蛋白E1以及介导细胞融合, 导致了肝细胞染色体成倍增加或非成倍增加, 引起染色体不稳定性及细胞周期紊乱, 从而促进肝细胞的致癌转化. |
出版日期 |
2023-04-28 11:04 |
引文著录 |
施旭佳, 尧晨光, 李涵泺, 魏艳红, 胡康洪. HBV慢性感染诱导的染色体超倍化及靶向治疗策略. 世界华人消化杂志 2023; 31(8): 299-306 |
URL |
https://www.wjgnet.com/1009-3079/full/v31/i8/299.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v31.i8.299 |
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